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| FACTORS INFLUENCING SERUM PEPSINOGEN LEVELS IN A CHINESE POPULATION AT HIGH RISK OF STOMACH CANCER | |
| 引用本文： | 昌云生,游伟程,张联,赵雷,马骏岭,刘宪秋,刘伟东,RobertW.Kneller,张劲松,MichealI.Samloff,WilliamJ.Blot. FACTORS INFLUENCING SERUM PEPSINOGEN LEVELS IN A CHINESE POPULATION AT HIGH RISK OF STOMACH CANCER[J]. 中国癌症研究, 1993, 5(3): 157-164. DOI: 10.1007/BF02997515 |
| 作者姓名： | 昌云生 游伟程 张联 赵雷 马骏岭 刘宪秋 刘伟东 RobertW.Kneller 张劲松 MichealI.Samloff WilliamJ.Blot |
| 作者单位： | Weifang Medical Institute，Weifang 261041，Shandong，China，Beijing Institute far Cancer Research，Beijing 100034，Beijing Institute far Cancer Research，Beijing 100034，Beijing Institute far Cancer Research，Beijing 100034，Weifang Medical Institute，Weifang 261041，Shandong，China，Beijing Institute far Cancer Research，Beijing 100034，Linqu Public Health Bureau，Lmqu 252600，Shandong，China，Verterans Administration Medical Center，Sepulveda，CA，USA 91343，Beijing Institute far Cancer Research，Beijing 100034，Verterans Administration Medical Center，Sepulveda，CA，USA 91343，National Cancer Institute，Betheada，Maryland，USA 20892 |
| 摘 要： | The relationships between serum pepsinogen (PG) levels and age, sex, ABO blood type, cigarette smoking and diet were studied among over 3, 000 residents selected at random in an area with high risk of stomach cancer in Shandong Province, China. Males had significantly higher median PG Ⅰ and Ⅱ levels than feamles. PG Ⅰ tended to decrease and PG Ⅱ to rise with age. Subjects with blood type A had a higher PG Ⅱ level than subjects with other blood types. Both PG Ⅰ and Ⅱ levels rose with dally consumption of cigarettes. Alcohol consumption was not related to PG levels. The PG Ⅰ/Ⅱ ratio declined with increasing consumption of sour pancakes, a fermented staple food found to contain N-nitroso compounds and to be a risk factor for stomach cancer in this population. |
Factors influencing serum pepsinogen levels in a Chinese population at high risk of stomach cancer |
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| Yunsheng Chang,Weicheng You,Lan Zhang,Lei Zhao,Junling Ma,Xianqiu Liu,Weidong Liu,Robert W. Kneller,Jinsong Zhang,Micheal I. Samloff,William J. Blot. Factors influencing serum pepsinogen levels in a Chinese population at high risk of stomach cancer[J]. Chinese Journal of Cancer Research, 1993, 5(3): 157-164. DOI: 10.1007/BF02997515 | |
| Authors: | Yunsheng Chang Weicheng You Lan Zhang Lei Zhao Junling Ma Xianqiu Liu Weidong Liu Robert W. Kneller Jinsong Zhang Micheal I. Samloff William J. Blot |
| Affiliation: | Chang Yunsheng You Weicheng Zhang Lan Zhao LeiMa Junling Liu Xianqiu Liu Weidong Robert W. KnellerZhang Jinsong Micheal I. Samloff William J. BlotWeifang Medical Institute,Weifang 261041,Shandong,China Beijing Institute far Cancer Research,Beijing 100034,China Linqu Public Health Bureau,Lmqu 252600,Shandong,China National Cancer Institute,Betheada,Maryland,USA 20892 Verterans Administration Medical Center,Sepulveda,CA,USA 91343 |
| Abstract: | The relationships between serum pepsinogen (PG) levels and age, sex, ABO blood type, cigarette smoking and diet were studied among over 3, 000 residents selected at random in an area with high risk of stomach cancer in Shandong Province, China. Males had significantly higher median PG I and II levels than feamles. PG I tended to decrease and PG II to rise with age. Subjects with blood type A had a higher PG II level than subjects with other blood types. Both PG I and II levels rose with daily consumption of cigarettes. Alcohol consumption was not related to PG levels. The PG I/ II ratio declined with increasing consumption of sour pancakes, a fermented staple food found to contain N-nitroso compounds and to be a risk factor for stomach cancer in this population. |
| Keywords: | Serum pepainogen Stomach cancer Risk factors. |
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