| 海洋来源的荧光天然产物 |
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| 引用本文： | 朱丹阳,姜永贺,蒋宏飞,于日磊,江涛.海洋来源的荧光天然产物[J].中国海洋药物,2019,38(4):58-64. |
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| 作者姓名： | 朱丹阳 姜永贺 蒋宏飞 于日磊 江涛 |
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| 作者单位： | 中国海洋大学海洋药物教育部重点实验室,中国海洋大学海洋药物教育部重点实验室,中国海洋大学海洋药物教育部重点实验室,中国海洋大学海洋药物教育部重点实验室,中国海洋大学海洋药物教育部重点实验室 |
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| 基金项目： | “蓝色药库”技术创新工程,山东省重大科技创新专项,(No2018SDKJ0403-2)、“青岛海洋科学与技术国家实验室鳌山科技创新计划项目(No.2015ASKJ02)”资助 |
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| 摘 要： | 近年来海洋天然产物越来越引起科学家们的关注。由于在珊瑚礁珊瑚和海葵等海洋无脊椎动物中具有荧光现象普遍,许多海洋天然产物除了药用和生物学价值外,还具有突出的荧光特性。本文从来源、发色团结构以及应用等方面进行综述,介绍了Ageladine A、Marmycin A、两种新型羟基蒽醌和Zoanthoxanthins等几种海洋来源的荧光小分子,以及代表性的海洋荧光蛋白GFP家族和藻胆蛋白。它们具有独特的光学性质将在生物医学领域广泛应用。
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| 关 键 词： | 海洋荧光天然产物 海洋荧光小分子 海洋荧光蛋白 |
| 收稿时间： | 2019/3/5 0:00:00 |
| 修稿时间： | 2019/4/24 0:00:00 |
Marine Fluorescent Natural Product |
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| ZHU Dan-Yang,JIANG Yong-He,JIANG Hong-Fei,YU Ri-Lei and JIANG Tao.Marine Fluorescent Natural Product[J].Chinese Journal of Marine Drugs,2019,38(4):58-64. |
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| Authors: | ZHU Dan-Yang JIANG Yong-He JIANG Hong-Fei YU Ri-Lei and JIANG Tao |
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| Institution: | Key Laboratory of Marine Drugs,Ministry of Education of China,School of Pharmacy,Ocean University of China,Key Laboratory of Marine Drugs,Ministry of Education of China,School of Pharmacy,Ocean University of China,Key Laboratory of Marine Drugs,Ministry of Education of China,School of Pharmacy,Ocean University of China,Key Laboratory of Marine Drugs,Ministry of Education of China,School of Pharmacy,Ocean University of China,Key Laboratory of Marine Drugs,Ministry of Education of China,School of Pharmacy,Ocean University of China |
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| Abstract: | Marine natural products have increasingly captured the attention of scientists in the past few decades. In addition to the medicinal and biological values, many marine natural products also have outstanding fluorescent properties. Fluorescence is very common in marine invertebrates such as corals and sea anemones. This review will summarize several marine-derived fluorescent molecules including ageladine A, marmycin A, zoanthoxanthins and the representative marine fluorescent proteins, GFP family and phycobiliproteins. They have unique optical properties and are widely used in biomedicine. |
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| Keywords: | marine fluorescent natural product marine fluorescent small molecule marine fluorescent protein |
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