| 人类线粒体DNA多态性及其应用的研究进展 |
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| 引用本文： | 朱颖婷,程慧华,金颖,徐开轶,夏之秋,漆微韡,骆晓枫. 人类线粒体DNA多态性及其应用的研究进展[J]. 国际遗传学杂志, 2009, 32(6). DOI: 10.3760/cma.j.issn.1673-4386.2009.06.009 |
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| 作者姓名： | 朱颖婷 程慧华 金颖 徐开轶 夏之秋 漆微韡 骆晓枫 |
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| 作者单位： | 中山大学中山医学院临床医学一系,广州,510080;中山大学基础医学实验教学中心分子医学实验室,广州,510080 |
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| 基金项目： | 中山大学实验室开放基金 |
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| 摘 要： | 线粒体DNA是惟一分布于核外的遗传物质,呈严格母系遗传,突变率高且积累量大,因此人类线粒体DNA的遗传多态性对于个体识别、种族遗传关系分析、亲缘关系鉴定等具有重要意义,本文对人类线粒体DNA多态性应用于以上方面的研究进展以予综述.
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| 关 键 词： | 线粒体DNA 多态性 |
The Research and Application Development of Human Mitochondrial DNA Polymorphism |
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| ZHU Ying-ting,CHENG Hui-hua,JING Ying,XU Kai-yi,XIA Zhi-qiu,QI Wei-wei,LUO Xiao-feng. The Research and Application Development of Human Mitochondrial DNA Polymorphism[J]. International JOurnal of Genetics, 2009, 32(6). DOI: 10.3760/cma.j.issn.1673-4386.2009.06.009 |
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| Authors: | ZHU Ying-ting CHENG Hui-hua JING Ying XU Kai-yi XIA Zhi-qiu QI Wei-wei LUO Xiao-feng |
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| Abstract: | Mitochondrial DNA (mtDNA) is the unique extranuclear genome of human being, and strictly maternally inherited. Mitochondrial DNA has high mutation rate and substantial accumulation of mutation. Therefore, the polymorphism of mtDNA plays an important role in the study of individual identity, population relationship, and consanguinity identification, etc, which will be discussed in details. |
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| Keywords: | Mitochondrial DNA Polymorphism |
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