艾滋病合并多重耐药菌感染患者临床特点分析与对策

目的分析艾滋病合并多重耐药菌感染患者的临床特点下,提出对策。方法对1 394例艾滋病患者住院期间多重耐药菌感染资料进行分析,观察多重耐药菌感染率、感染部位,统计多重耐药菌种类构成比、免疫学指标构成比。结果 1 394例艾滋病患者发生多重耐药菌感染20例,发病率1.43%;感染部位以肺部感染发生率最高,为65%;感染菌种主要是产超广谱β-内酰胺酶,占比85%;20例患者外周血CD4+T细胞计数水平全部低于正常。结论住院艾滋病患者存在合并多重耐药菌感染风险,制定多重耐药防控管理措施,提高患者生存率。

Analysis on clinical features of HIV patients with multiple drug-resistant bacterial infections and strategies

Objective To analyze the clinical features of HIV patients with multiple drug-resistant bacterial infections to find out corresponding measures.Method Analyze 1 394 HIV patients on multiple drug-resistant bacterial infectionsduring hospitalization.Observe ratio of multiple drug-resistant bacterial infections,infection position,constituent ratio of bacterial species and immunological indexes.Result 20 （1.43％） among 1 394 HIV patients are observed to have multiple drug resistant bacterial infections.65％ infections happen in lung,which is the highest among all positions.85％ infec tions are caused by extended spectrum β-lactamase （ESBLs）.Peripheral CD4＋T cell count of all 20 patients are lower than normal.Conclusion HIV inpatients have a high risk of multiple drug-resistant bacterial infections.Prevention meas ures on multiple drug resistant bacterial infections can improve survival rate for patients.