Occurrence of melanoma in "dysplastic" nevus spilus: report of case and analysis by flow cytometry |
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| Authors: | R. S. Kurban F. I. Preffer A. J. Sober M. C. Mihm Jr. R. L. Barnhill |
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| Affiliation: | Pathology Department, Massachusetts General Hospital, Harvard Medical School, Boston. |
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| Abstract: | We report a case of melanoma arising in a large nevus spilus. On histologic examination, the nevus spilus had diagnostic features of melanocytic dysplasia. Further characterization by flow cytometry showed DNA-aneuploidy within the melanoma as well as in one of the darker pigmented papules within the nevus spilus. The significance of this finding and a review of melanomas originating in nevi spili are presented. |
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