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Human IgG Fc-binding phage antibodies constructed from synovial fluid CD38+ B cells of patients with rheumatoid arthritis show the imprints of an antigen-dependent process of somatic hypermutation and clonal selection
Authors:Van Esch W J E  Reparon-Schuijt C C  Hamstra H J  Van Kooten C  Logtenberg T  Breedveld F C  Verweij C L
Affiliation:Department of Rheumatology, Leiden University Medical Centre, Leiden, The Netherlands.
Abstract:
Keywords:rheumatoid arthritis  synovial fluid plasma cells  phage display  rheumatoid factor activity  sequence analysis
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