鲍曼不动杆菌的临床分离及其耐药性分析

目的 分析鲍曼不动杆菌（Ab）对抗菌药物的耐药性,以指导临床医师合理用药. 方法 应用法国生物-梅里埃ATB Expression型全自动鉴定等系统分析我院2009年1月1日至2010年2月28日住院患者分离出的56株Ab,对其分离率,耐药性进行分析. 结果 总分离率分别为：2009年1～4月1.25%（9/720）;2009年5～10月2.07%（15/726）;2009年11月至2010年2月4.34%（32/738）.其中重症监护室在各病区占的比例较高,百分比为53.6%,该菌在临床各种标本中的分布情况以百分比计其中痰标本高达87.5%. 结论 Ab目前对多黏菌素E无耐药,对亚胺培南、美罗培南敏感,对其他抗菌药物已高度耐药;重视细菌培养、合理使用抗菌药物有利于控制耐药菌的产生.

Acinetobacter baumannii infections and drug resistance analysis of clinical isolates

Objective To analyze Acinetobacter baumannii(Ab)infection and antibacterial drug resistance to guide clinical drug usage. Methods ATB Expression was used to analyze drug sensitivity of patients hospitalized during January 1 st,2009 to February 28th,2010. Results Fifty-six strains of Ab were isolated in this period,while 53.6% of them were isolated from the intensive care unit.Ab was detected mostly from phlegm and the percentage was 87.50%. Conclusions Ab does not tolerate Polymyxin E and is sensitive to Imipenem and Meropenem,butit has high tolerance to other antibacterials.Clinically attaching the importance of bacteria culture and using antibacteria agents reasonably could prevent the increasing resistant organism.