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| 睡眠剥夺对记忆功能的影响机制及药物干预研究进展 | |
| 引用本文： | 蒋超,殷智宇,徐莉春. 睡眠剥夺对记忆功能的影响机制及药物干预研究进展[J]. 现代医药卫生, 2012, 28(1): 85-86 |
| 作者姓名： | 蒋超 殷智宇 徐莉春 |
| 作者单位： | 1. 徐州医学院公共卫生学院2008级预防班,江苏徐州,221004 2. 徐州医学院麻醉学院2008级灌注班,江苏徐州,221004 3. 徐州医学院公共卫生学院毒理学教研室,江苏徐州,221004 |
| 基金项目： | 江苏省大学生实践创新训练计划项目基金(994) |
| 摘 要： | 睡眠剥夺(sleep deprivation,SD)对机体记忆的影响可通过多种机制实现.海马的突触可塑性是研究学习记忆机制的重要目标,长时程增强(long-term potentiation,LTP)和长时程抑制(long-termdepression,LTD)是突触可塑性重要的功能指标,因而与SD造成的记忆损伤有关. |
| 关 键 词： | 睡眠剥夺 记忆 长时程增强 长时程抑制 |
Research progress in influencing mechanism of sleep deprivation on memory function and drug intervention |
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| JIANG Chao , YIN Zhi-yu , XU Li-chun. Research progress in influencing mechanism of sleep deprivation on memory function and drug intervention[J]. JOURNAL OF MODERN MEDICINE & HEALTH, 2012, 28(1): 85-86 | |
| Authors: | JIANG Chao YIN Zhi-yu XU Li-chun |
| Affiliation: | 1.Class Prevention Grade 2008,Public Health College,Xuzhou Medical College,Xuzhou,Jiangsu 221004,China;2.Class Perfusion,Grade 2008,Anesthesiology College,Xuzhou Medical College,Xuzhou,Jiangsu 221004,China;3.Department of Toxicology,Public Health College,Xuzhou Medical College,Xuzhou,Jiangsu 221004,China) |
| Abstract: | The influence of sleep deprivation(SD) on the memory function can be realized through a variety of mech-anisms.Hippocampal synaptic plasticity is the important target of the mechanisms of learning and memory,long-term potentia-tion(LTP)and long-term depression(LTD) are the important functional indicators of synaptic plasticity,thus,which is related with memory impairment caused by SD. |
| Keywords: | Sleep deprivation Memory Long-term potentiation(LTP) Long-term depression(LTD) |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |