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| HPLC法测定注射用头孢唑林钠中头孢唑林的含量 | |
| 引用本文： | 郑风敏. HPLC法测定注射用头孢唑林钠中头孢唑林的含量[J]. 中国民族民间医药杂志, 2014, 0(17): 8-8 |
| 作者姓名： | 郑风敏 |
| 作者单位： | 河南省鹤壁市食品药品检验所,河南鹤壁458030 |
| 摘 要： | 目的:建立注射用头孢唑林钠中头孢唑林的含量测定方法。方法:HPLC法,C18柱(4.6×150mm,5μm),流动相:乙腈-磷酸氢二钠、枸橼酸溶液(13∶87);流速:1.0 ml/min;检测波长:254nm;柱温:25℃;进样量:10μl。结果:头孢唑林在浓度40～200μg/ml的范围内有良好的线性关系(r=0.9999)。结论:该法简单,专属性强,准确度高,便于对注射用头孢唑林钠的质量控制。 |
| 关 键 词： | HPLC 头孢唑林 含量测定 |
Determination of cefazolin sodium for injection by HPLC |
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| ZHENG Feng-min. Determination of cefazolin sodium for injection by HPLC[J]. Chinese Journal of Ethnomedicine and Ethnopharmacy, 2014, 0(17): 8-8 | |
| Authors: | ZHENG Feng-min |
| Affiliation: | ZHENG Feng-min (Hebi Institute for Food and Drug Control, Hebi 458030, China) |
| Abstract: | Objective To estabilish a method for the determination of cefazolin sodium for injection. Method HPLC C18 （4. 6 ×150mm, 5μm） column was used with acetonitrile- disodium hydrogen phosphate and citric Acid （ 13： 87） . The flow rate was 1.0 ml/min. The detection wave length was 254nm. The column temperature was at 25℃ , and the inject volume was 10μl. Results The linearities of cefazolin sodium were obtained separately over the rang of were 40 -200μg/ml （r =0. 9999） o Conclusion This Method is simple, accurate, and could be adopted for the quality control of this durg. |
| Keywords: | HPLC cefazolin sodium determination |
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