异体巩膜移植在眼睑再造中的应用

选择1996-08/2004-10滨州医学院附属医院眼科收治的异体巩膜移植治疗上眼睑恶性肿瘤切除后眼睑全缺损患者22例（22眼）。采用乙醇保存的异体巩膜代替睑板，对上眼睑恶性肿瘤切除术后眼睑全缺损患者行眼睑再造术。残留的穹隆部结膜移行覆盖于异体巩膜内侧面，左右两侧缝线固定于睑板残端或内外眦韧带处，眼轮匝肌和皮肤一起向睑缘部牵拉覆盖于异体巩膜表面，行睑裂缝合，半年后睑缘部切开。术后所有患者均得到随访，随访时间平均28.8个月。均未见排斥反应，眼睑闭合良好，外观满意。异体巩膜移植代替睑板行眼睑再造术，能保持眼睑良好的功能和外观。

Application of scleral allograft transplantation in eyelid reconstruction

From August 1996 to October 2004, totally 22 patients (22 eyes) of entire blepharocoloboma after malignant palpebrae superior tumorectomy, admitted to Department of Ophthalmology in the Affiliated Hospital of Binzhou Medical College, were repaired with sclera transplantation for the eyelid reconstruction. The alcohol-preserved scleral allograft was utilized for a substitute of tarsal plate. The internal surface of scleral graft was covered with remaining fornical conjunctiva and the external surface with musculus orbicularis oculi and skin. Bilateral sutures were fixed on the stump of tarsal plate or exterior and interior external palpebral ligament. Then eyelid margin was sutured and cut off after 6 months. All patient were followed up after operation for average 28.8 months. No reject reaction was found, catacleisis was fine and external appearance was satisfying. The eyelid reconstruction with scleral allograft is effective to keep eyelid normal function and external appearance.