| 叶酸对结直肠腺瘤性息肉的影响 |
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| 引用本文： | 高占娟,胡晓娜. 叶酸对结直肠腺瘤性息肉的影响[J]. 胃肠病学, 2012, 17(6): 366-368 |
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| 作者姓名： | 高占娟 胡晓娜 |
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| 作者单位： | 复旦大学附属华东医院消化内科,200040 |
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| 摘 要： | 叶酸是广泛存在于绿叶蔬菜中的水溶性B族维生素，在DNA的合成和复制中起重要作用。研究显示在正常结直肠黏膜中，叶酸缺乏易导致腺瘤性息肉发生；如结直肠腺瘤性息肉已形成，叶酸补充可能增加其进展风险。800μg/d的适量叶酸摄入是有益的，应不会增加结直肠腺瘤性息肉的发生风险。
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| 关 键 词： | 叶酸 结直肠 腺瘤性息肉 |
Effect of Folate on Colorectal Adenomatous Polyps |
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| GAO Zhanjuan , HU Xiaona. Effect of Folate on Colorectal Adenomatous Polyps[J]. Chinese Journal of Gastroenterology, 2012, 17(6): 366-368 |
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| Authors: | GAO Zhanjuan HU Xiaona |
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| Affiliation: | .Department of Gastroenterology,Huadong Hospital Affiliated to Fudan University,Shanghai(200040) |
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| Abstract: | Folate,a water-soluble B vitamin,is widely existed in green leafy vegetables.It plays important role in DNA synthesis and replication.Studies have demonstrated that lack of folate in normal colorectal mucosa appears to predispose to neoplastic transformation.However,if the colorectal neoplasms have already established,folic acid supplementation has a tumor promotion effect.Modest level(800μg/d) of folic acid supplementation is considered to be beneficial and may not increase the risk of colorectal adenomatous polyps. |
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| Keywords: | Folic Acid Colon and Rectum Adenomatous Polyps |
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