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髋关节置换术后隐性失血的新进展
引用本文:袁磊,包倪荣,赵建宁.髋关节置换术后隐性失血的新进展[J].中国骨伤,2015,28(4):378-382.
作者姓名:袁磊  包倪荣  赵建宁
作者单位:南京大学医学院附属金陵医院骨科, 江苏 南京 210000;南京大学医学院附属金陵医院骨科, 江苏 南京 210000;南京大学医学院附属金陵医院骨科, 江苏 南京 210000
基金项目:江苏省临床医学科技专项资助(编号:BL2012002)
摘    要:人工髋关节置换术(total hip arthroplasty,THA)是目前髋关节终末疾病的重要治疗手段。术后常存在大量隐性失血,严重影响患者的术后康复。如何从根本上预防和减少THA术后隐性失血量,是亟待解决的问题。麻醉、年龄、性别、体重指数及抗凝药物的使用是THA手术失血的潜在因素,但其隐性失血的发生机制仍然不清。氨甲环酸在预防围手术期失血中的作用显着,今后有必要对隐性失血与纤溶机制的关联性进行证实,这对完善隐性失血的发生机制具有积极的意义。

关 键 词:关节成形术  置换    手术后出血  综述文献
收稿时间:2014/7/29 0:00:00

Progress on hidden blood loss after hip replacement
YUAN Lei,BAO Ni-rong and ZHAO Jian-ning.Progress on hidden blood loss after hip replacement[J].China Journal of Orthopaedics and Traumatology,2015,28(4):378-382.
Authors:YUAN Lei  BAO Ni-rong and ZHAO Jian-ning
Institution:Department of Orthopaedics, Jinling Hospital Affiliated to Medical School of Nanjing University, Nanjing 210000, Jiangsu, China;Department of Orthopaedics, Jinling Hospital Affiliated to Medical School of Nanjing University, Nanjing 210000, Jiangsu, China;Department of Orthopaedics, Jinling Hospital Affiliated to Medical School of Nanjing University, Nanjing 210000, Jiangsu, China
Abstract:Total hip arthroplasty(THA) is a vital therapeutic tool for hip terminal disease. Frequently, hidden blood loss exists in the postoperation, which seriously affect the postoperative rehabilitation of patients. It is urgent need to solve the problem that how to fundamentally prevent and reduce hidden blood loss after THA. Although THA has its own operational reason in blood loss, and also relates to a variety of risk factors, the mechanism of hidden blood loss is not clear. Tranexamic acid has a significant role in preventing perioperative blood loss, and the correlation of hidden blood loss and fibrinolytic mechanism would be confirm necessarily in the future, which will produce positive significance in completing the mechanism of hidden blood loss.
Keywords:Arthroplasty  replacement  hip  Postoperative hemorrhage  Review literature
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