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HLA-frequencies of Austrian umbilical cord blood samples
Affiliation:1. Vivocell Biosolutions, Graz, Austria;2. Institute of Human Genetics, Medical University of Graz, Austria;3. Department for Mathematics and Scientific Computing, Karl-Franzens-University Graz, Austria
Abstract:We investigated HLA-A, HLA-B, and HLA-DRB1 gene frequencies in 1368 unrelated Austrian umbilical cord blood samples. HLA-C gene frequencies were investigated in a subgroup of 503 samples. HLA typing was performed via sequenced-based typing (SBT). The aim of this study was to examine the HLA diversity in a large Austrian population sample. In addition we present results of a subsample of 100 samples at a subtype level. This study is the first systematic investigation of donated umbilical cord blood samples in the Austrian population.
Keywords:HLA  Haplotype and allele frequencies  High-resolution typing  Umbilical cord blood  Austrian population
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