Genotoxicity studies of glycidol fatty acid ester (glycidol linoleate) and glycidol期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Genotoxicity studies of glycidol fatty acid ester (glycidol linoleate) and glycidol

Authors:	Naohiro Ikeda Kenkichi FujiiMiko Sarada Hitoshi SaitoMasayoshi Kawabata Kiyoko NaruseKatsuyuki Yuki Hideaki NakagiriHiroshi Honda Yasushi TamakiNaohiro Nishiyama Toshio Kasamatsu

Affiliation:	Global R&D Safety Science, Kao Corporation, 2606 Akabane, Ichikai-Machi, Haga-Gun, Tochigi 321-3497, Japan; BML, INC., 1361-1 Matoba, Kawagoe-Shi, Saitama 350-1101, Japan; Mitsubishi Chemical Medience Corporation, 14 Sunayama, Kamisu-Shi, Ibaraki 314-0255, Japan

Abstract:	Glycidol fatty acid esters (GEs) are found in refined edible oils. Safety concerns have been alleged due to the possible release of glycidol (G), an animal carcinogen.

Keywords:	CP, cyclophosphamide monohydrate G, glycidol GEs, glycidol fatty acid esters GLP, Good Laboratory Practice OECD, Organization for Economic Co-operation and Development MN, micronucleus ME, mature erythrocyte IME, immature erythrocyte MNIME, micronucleated IME MMS, methyl methanesulphonate ENNG, N-Ethyl-N-nitro-N-nitrosoguanidine 2NF, 2-nitrofluorene AF-2, 2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide 2AA, 2-aminoanthracene 9AA, 9-aminoacridine hydrochloride hydrate NaN₃, sodium azide CMC-Na, carboxymethyl cellulose sodium aqueous solution MMC, mitomycin C B(a)P, benzo(a)pyrene
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