| 血清MMP-9、hsCRP在急性冠脉综合征患者中的变化及意义 |
| |
| 引用本文： | 李轶男,郑伟. 血清MMP-9、hsCRP在急性冠脉综合征患者中的变化及意义[J]. 中国实用医药, 2008, 3(14): 34-35 |
| |
| 作者姓名： | 李轶男 郑伟 |
| |
| 作者单位： | 1. 110000,沈阳,中国医科大学
2. 辽宁省辽阳市第二人民医院检验科,111000 |
| |
| 摘 要： | 目的观察急性冠脉综合征(ACS)患者外周血中基质金属蛋白酶-9(MMP-9)及超敏C反应蛋白(hsCRP)的水平变化。方法选取110例ACS患者,以40例非ACS患者作为对照组,采用酶联免疫法(ELISA)测定血清MMP-9的水平,采用免疫比浊法定量检测hsCRP。结果ACS组MMP-9、hsCRP水平显著高于对照组分别为〔(14.25±3.51)和(11.14±2.23)ng/ml,P<0.01;(4.32±2.41)和(0.23±0.11)mg/100 ml,P<0.01〕。结论急性冠脉综合征患者存在明显的炎性反应,MMP-9和hsCRP的高表达可佐证急性冠脉综合征。
|
| 关 键 词： | 急性冠脉综合征 基质金属蛋白酶9 超敏C反应蛋白 |
Changes and implication of serum matrix metalloproteinase-9 and high secitivity C-reactive protein(hsCRP) in patients with acute coronary syndromes |
| |
| LI Yi-nan,ZHENG Wei. Changes and implication of serum matrix metalloproteinase-9 and high secitivity C-reactive protein(hsCRP) in patients with acute coronary syndromes[J]. China Practical Medical, 2008, 3(14): 34-35 |
| |
| Authors: | LI Yi-nan ZHENG Wei |
| |
| Abstract: | Objective To investigate changes of serum matrix metalloproteinase-9(MMP-9) and high secitivity C-reactive protein(hsCRP) in patients with acute coronary syndromes(ACS).Methods Using enzyme-linked immunosorbent assay(ELISA) and scatter rate nephelometry,serum MMP-9 and hsCRP were messured in 110 patients with ACS and 40 patients without ACS.Results The serum levels of MMP-9 and hsCRP were significantly higher than those in control groups(P<0.01).Conclusion Inflammation may be present significantly in patients with ACS.Serum MMP-9 and hsCRP may provide valuable evidence in the diagnosis of ACS. |
| |
| Keywords: | Acute coronary syndrome Matrix metalloproteinase-9 High sensitivity C-reactive protein |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
