沧州地区城镇居民高血压患者脂代谢特点研究

目的分析不同年龄与性别之间高血压病患者血压和血脂的关系与特点,了解高血压病患者血脂最新动态,为临床防治高血压提供依据。方法 4 923例居民中962例高血压患者按随机分层抽样调查方法,分析高血压患者不同年龄、不同血压级别脂代谢状况及高血脂的相关因素。结果①总胆固醇(TC)、三酰甘油(TG)和低密度脂蛋白(LDL)随年龄增长总体趋势为先升后降,男性高峰为51～60岁,女性高峰在61～70岁,男女性别间比较有显著性差异(P<0.01)。②各年龄组男性患者高密度脂蛋白胆固醇(HDL-C)均低于女性。③全部高血压患者随年龄增加收缩压升高,舒张压下降。④高血压患者较正常血压者血脂较高,且随血压升高血脂有上升趋势。⑤高血压患者血脂代谢异常组糖代谢异常及肥胖所占比例更高。结论高血压患者随年龄增长血脂有先增高后下降趋势,男性血脂高峰多在60岁以前,女性多在60岁以后,高峰水平女性较男性约晚10 a;随血压升高血脂也有上升趋势;血脂异常者发生糖代谢异常及肥胖比例更高。

Study on characteristics of blood fat in Cangzhou area town resident with high blood pressure

Objective It is to analyzing the relationship and characteristics between blood pressure and blood fat of hypertension patients with different age and sex,understanding the latest developments of the blood fat in the patients,providing the basis for clinical prevention and treat. Methods Nine hundred and sixty-two patients with high blood pressure using random sampling stratification survey in 4923 cases of residents,analyzing the related factors of fat metabolism and high blood fat in hypertension patients with different age groups and different blood pressure levels. Results ①The tendency of TC,TG,LDL changes were descending after increasing,reached the peak values at the age of 51-60 years of age in men and 61-70 years of age in women,there were significant differences between different sex(P<0.01).②The level of HDL-C was higher in women than that in men of every age group.③All patients with high blood pressure were underwent systolic blood pressure elevates,diastolic pressure drops with age increasing.④The blood fat was higher in high blood pressure than normal blood pressure patients,and it was rose with elevated blood pressure.⑤ Sugar metabolism disorders,obesity were higher proportion in patients with high blood pressure and blood lipid metabolic abnormalities. Conclusion Patients with high blood pressure,blood fat has increased trend with age increasing,Men blood lipid peak many before the age of sixty,women in more than 60 years later,peak level is about 10 years later in women than men,with increased blood pressure,blood fat has rising trend;an person with blood lipid metabolic abnormalities has a high incidence of blood sugar metabolism disorders and obesity.