成分输血对产科急性弥散性血管内凝血患者凝血功能及治疗效果的影响

目的探讨成分输血对产科急性弥散性血管内凝血(DIC)患者凝血功能及治疗效果的影响。方法回顾性分析66例采取综合治疗措施救治的产科急性DIC者的临床资料,根据输血方式的不同分为成分输血的观察组(34例)和全血输血的对照组(32例),比较两组凝血功能指标、治疗效果、不良反应。结果观察组PLT、Fbg明显高于对照组,PT、a PTT明显低于对照组(t=2.843~27.343,P0.01,P0.05);观察组抢救成功率明显高于对照组(χ~2=4.128,P0.05),子宫全切率明显低于对照组(χ~2=4.686,P0.05);观察组不良反应(8.82%)明显低于对照组(28.13%)(χ~2=4.128,P0.05)。结论成分输血有助于改善产科急性DIC患者的凝血功能,提高抢救成功率,降低不良反应。

The Impact of Blood Component Transfusion on Coagulation Function and Treatment Effect in Obstetric Patients with Acute Disseminated Intravascular Coagulation

Objective To study effect blood component transfusion on coagulation function and treat-ment effect in obstetric patients with acute disseminated intravascular coagulation ( DIC ) . Methods Retro-spective analysis clinical data of 66 cases patients with obstetric acute DIC,they were randomly divided into blood component transfusion observation group(34 cases) and whole blood transfusion control group(32 cases) according to the different way of transfusion:coagulation function index,therapeutic effect and adverse reac-tions were compared between two groups. Results observation group PLT,Fbg were significantly higher than that of control group,PT,aPTT were significantly lower than the control group(t=2. 843~27. 343,P<0. 01, P<0. 05);Rescue success rate were significantly higher than the control group(χ2 =4. 128,P<0. 05),hys-terectomy rate were significantly lower than the control group (χ2 =4. 686 , P <0. 05 ) , adverse reactions (8. 82%)was significantly lower than the control group(28. 13%) (χ2 =4. 128,P <0. 05). Conclusion Blood component transfusion help to improve coagulation function of obstetric patients with acute DIC c,im-prove the rescue success rate,reduce the adverse reaction.