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Role for gender in colorectal cancer risk: a Taiwan population-based study |
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| Authors: | Chia-Lin Chou Shih-Feng Weng Jen-Kou Lin Shih-Ching Chang |
| Affiliation: | 1. Division of General Surgery, Department of Surgery, Chi-Mei Medical Center, Tainan, Taiwan 2. Division of Colon & Rectal Surgery, Department of Surgery, Taipei Veterans General Hospital and National Yang-Ming University, No 201, Section 2, Shih-Pai Road, 11217, Taipei, Taiwan 3. Department of Medical Research, Chi Mei Medical Center, Tainan, Taiwan 4. Department of Hospital and Health Care Administration, Chia-Nan University of Pharmacy and Science, Tainan, Taiwan |
| Abstract: | Background and aimsGender differences in the prognosis of colorectal cancer (CRC) remain controversial. The aim of this study was to complete a comprehensive analysis of gender differences in CRC survival derived from population registries in Taiwan.Materials and methodsWe analyzed survival data for patients diagnosed with CRC between 1998 and 2005 derived from the Taiwan Cancer Registry database. During this time period, 65,113 patients were registered, and 62,060 patients were eligible. Gender differences in overall survival and cancer-specific survival were analyzed by use of the Kaplan–Meier method. We then modeled the risk in different genders by use of a multivariate proportional hazard (Cox) model adjusting for possible confounders of survival.ResultsThe 5-year period overall and cancer-specific survivals were significantly higher in women than in men [51.84 % (95 % confidence interval (CI), 51.22–52.46) vs. 47.68 % (95 % CI, 47.14–48.22), log-rank p?p?p?Conclusions Our findings suggest that overall and cancer-specific survival advantage was most evident in women between 50 and 80 years of age. |
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