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Parental support buffers the association of depressive symptoms with cortisol and C-reactive protein during adolescence
Affiliation:1. University of Florida, 1329 SW 16th Street, Gainesville, FL 32608, United States;2. University of Colorado Anschutz Medical Campus, Mail Stop #F561, Children''s Eating Laboratory, 12631 E 17th Ave, Rm #2609, Aurora, CO 80045, United States;3. Colorado State University, 234 Gifford Building, Fort Collins, CO 80523, United States;4. Box 43011, Texas Tech University, Lubbock, TX 79409, United States;5. Brown University, School of Public Health, Box G-S121-8, Providence, RI 02912, United States;6. 530 41st St., Boulder, CO 80305, United States;7. University of Alabama at Birmingham, 227K Ryals Public Health Building, 1665 University Boulevard, Birmingham, AL 35294, United States;8. University of Florida, 2004 Mowry Rd, PO Box 100147, Gainesville, FL 32610, United States;9. University of Florida, PO Box 100165, Gainesville, FL 32610, United States;10. 4201 Social and Behavioral Sciences Gateway, University of California Irvine, Irvine, CA 92697, United States;11. Anschutz Health and Wellness Center, 12348 E. Montview Blvd., Mailstop C263, Aurora, CO 80045, United States;12. University of Alabama at Birmingham, 140J Ryals Public Health Building, 1665 University Boulevard, Birmingham, AL 35294, United States
Abstract:
Social experiences can affect the relationship between depression and physical health. The current study examined how social support from parents and friends may moderate the association of depressive symptoms with hypothalamic-pituitary-adrenal (HPA) axis activity and C-reactive protein among adolescents (N = 316, Mage = 16.40, SD = .74; 57% female) from diverse ethnic backgrounds (23.1% Asian, 29.1% European, 41.8% Latino, and 6.0% other backgrounds). Results indicated that parent support, but not friend support, moderated the link between depressive symptoms and both total daily cortisol output (a measure HPA activity) and C-reactive protein (a marker of inflammation). These patterns did not differ by ethnicity. Overall, the study highlights the continued, and perhaps accumulated, importance of parents during adolescence despite increasing needs for autonomy from and exploration outside of the family unit.
Keywords:Depressive symptoms  Social support  Inflammation  Cortisol
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