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Stress-induced neuroinflammation is mediated by GSK3-dependent TLR4 signaling that promotes susceptibility to depression-like behavior
Institution:1. Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, Miami, FL 33136, United States;2. Department of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami, Miami, FL 33136, United States;3. Centro de Investigaciones Biologicas-CSIC, 28040 Madrid, Spain;4. Laboratoire Génomique, Bioinformatique et Applications, EA4627, Conservatoire National des Arts et Métiers, 75003 Paris, France;1. Lab of Stress Medicine, Department of Psychology and Mental Health, Second Military Medical University, Shanghai 200433, PR China;2. Team of Aviation Physical Examination, Air Force General Hospital of PLA, Beijing 100142, PR China;3. Department of Navy Medicine, Second Military Medical University, Shanghai 200433, PR China;1. Department of Neuroscience, OSU Wexner Medical Center, United States;2. Division of Biosciences, OSU College of Dentistry, United States;3. Institute for Behavioral Medicine Research, The Ohio State University, United States;1. Department of Psychology and Neuroscience, Center for Neuroscience, University of Colorado, Boulder, CO, USA;2. Institute for Behavioral Medicine Research, The Ohio State University, Columbus, OH, USA;1. Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut;2. Department of Physiology and Pharmacology, Des Moines University, Des Moines, Iowa;3. Division of Neuropsychiatry, Tottori University, Tottori, Japan;4. Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana;5. Lundbeck Research USA, Paramus, New Jersey;1. Department of Physiology, Second Military Medical University, Shanghai 200433, China;2. School of Kinesiology, The Key Laboratory of Exercise and Health Sciences of Ministry of Education, Shanghai University of Sport, Shanghai 200438, China
Abstract:
Keywords:Stress  Neuroinflammation  Depression  Toll-like receptor 4  Fluoxetine  Glycogen synthase kinase-3
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