聚桂醇注射治疗龟头静脉畸形15例临床分析

目的：评价经皮病损内注射聚桂醇治疗龟头静脉畸形的疗效及安全性。方法2011年1月至2013年5月，共治疗龟头部静脉畸形15例。采用硬膜外麻醉下经皮瘤体内注射聚桂醇硬化治疗，每次聚桂醇注射液0.5～2.0 mL局部注射，治疗间隔1个月，治疗1～4次。结果所有患者治疗部位均出现暂时性红斑和水肿，仅1例发生局部溃破，2例患者术后出现轻度疼痛，无出血、感染病例。随访1～3年，所有患者龟头静脉畸形病灶完全清除，未见复发，无色素改变、畸形和勃起功能障碍。结论经皮瘤体内注射聚桂醇硬化治疗龟头静脉畸形疗效确切、简便易行，且术后出血和感染发生率低，不影响阴茎外观和功能，建议作为龟头静脉畸形的首选治疗方法。

Clinical Analysis of Intralesional Lauromacrogol Injection for Venous Malformation of Glans Penis in 15 Cases

Objective To evaluate the therapeutic effect and safety of intralesional lauromacrogol injection in the treat-ment of venous malformation of glans penis. Methods From Jan 2011 to May 2013, 15 patients with venous malformation of the glans penis were treated with percutaneous intralesional injection of lauromacrogol. Injections were administrated under epidural anesthesia at a dose of 0.5-2.0 mL. Patients were treated once 2 months for 1 to 4 times. Results All the patients experienced transient erythema and edema without bleeding and infection, whereas local diabrosis occurred in only 1 patient. There were 2 patients complained of light pain after treatment. After followed up for 12 months to 3 years, all patients were cured without pigment alteration, abnormalities and erectile dysfunction. Conclusion It is considerd that intralesional in-jection with lauromacrogol is a safe and effective method for the treatment of venous malformation of the glans penis with no influence on appearance and function, which can be carried out easily and shows a low postoperative infection rate, so that it should be suggested as first choice of venous malformation in glans penis.