经颅多普勒发泡实验在筛查隐源性卒中合并卵圆孔未闭的应用价值

目的探讨经颅多普勒发泡实验(C-TCD)在筛查隐源性卒中合并卵圆孔未闭中的应用价值。方法回顾分析60例隐源性卒中患者,包括发病特点,既往史,检验检查,分析相关数据。结果 60例患者均明确诊断为急性脑梗死、短暂性脑缺血发作,行经颅多普勒超声发泡试验(c-TCD)发现,阳性33例,阴性27例,经食道超声心动(TEE)检查证实有26例合并心脏卵圆孔未闭,16例合并下肢静脉血栓形成。结论 PFO在隐源性卒中中为常见病因,但常规检查很难发现,本研究通过c-TCD初步筛查PFO,阳性率及敏感性高于TEE,特异性亦较高,对于隐源性卒中合并PFO,可作为病因筛查的首选。

Transcranial Doppler ultrasound foaming test (C-TCD) in the screening of cryptogenic stroke complicated with patent foramen ovale(PFO)

Objective To explore the application value of Transcranial Doppler ultrasound foaming test ( C-TCD) in the screening of cryptogenic stroke complicated with patent foramen ovale (PFO).Methods Retrospective analysis of 60 cases of cryptogenic stroke patients ,including the characteristics of disease ,past history and examination .Results All pa-tients were diagnosed with acute cerebral infarction and transient ischemic attack ,both via C-TCD,including 33 positive ca-ses and 27 negative cases ,those patients were confirmed by ultrasonic echocardiography ( TEE) examination of the esopha-gus with 26 cases with PFO,16 cases with lower limb venous thrombosis .Conclusion PFO is a common cause of crypto-genic stroke,but it is hard to find in a regular examination ,this study use C-TCD to screening the cryptogenic stroke with PFO,we found C-TCD had a higher positive rate ,sensitivity and a high specificity than the TEE .So we can first choose C-TCD for the cryptogenic stroke people who are suspected having merged PFO .