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扁桃酸栓与甲硝唑栓治疗阴道滴虫病的比较
引用本文:樊振民,孙毅贞,郑淑蓉,狄志义. 扁桃酸栓与甲硝唑栓治疗阴道滴虫病的比较[J]. 中国新药与临床杂志, 1996, 0(5)
作者姓名:樊振民  孙毅贞  郑淑蓉  狄志义
作者单位:西安医科大学新药研究开发公司,北京医科大学附属第一医院,陕西省妇幼保健医院
摘    要:目的:验证扁桃酸栓治疗阴道滴虫病的疗效。方法:阴道滴虫病病人150例,采用随机单盲法分成2组。治疗组100例(年龄34±s6a)用扁桃酸栓(100mg/粒),每晚临睡时放入阴道中1粒,疗程为4d。对照组50例(年龄34±6a)用甲硝唑栓(200mg/粒),每晚临睡时放入阴道中1粒,疗程为7d.结果:治疗组痊愈61%,显效29%,有效10%。对照组痊愈52%,显效40%,有效8%。2组疗效相似(P>0.05),且均未发现明显不良反应。结论:扁桃酸栓治疗阴道滴虫病疗效与甲硝唑栓相似。

关 键 词:扁桃酸,甲硝唑,阴道滴虫,阴道内投药

Mandelic acid suppository vs metronidazole suppository in treating Trichomonas vaginitis
FAN Zhen-Min,SUN Yi-Zhen. Mandelic acid suppository vs metronidazole suppository in treating Trichomonas vaginitis[J]. Chinese Journal of New Drugs and Clinical Remedies, 1996, 0(5)
Authors:FAN Zhen-Min  SUN Yi-Zhen
Abstract:AIM:To test and verify the therapeutic effect of mandelic acid suppOsitory in treating vaginal trichomoniasis.METHODS :One hundred and fifty patients with vaginal trichomoniasis were randomly and single-blindly divided into two groups,Testing group including 100 patients(age 34 ±s 6 a) received mandelic acid suppository (Supp) (100 mg/Supp) for 4d,and the other 50 patients(age 34 ±6 a) received metronidazole Supp(200 mg/Supp) for 7 d as control,each patient inserted a Supp into vagina before she went to bed.RESULTS:The cure rate of the testing group was 61%,remarkable effective rate 29% and effective rate 10%. The cure rate of the control group was 52%,remarkable effective rate 40% and effective rate 8%.Two groups had similar curative effect(P>0.05) ,and notable adverse reaction was not observed.CONCLUSION:The curative effect of mandilic acid supp in treating vaginal trichomoniasis is alike with metronidazole Supp.
Keywords:mandelic acid  metronidazole  Trichomonas vaginalis  intravaginal administration  
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