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Comparative Effectiveness of Pharmacologic Interventions for Pulmonary Arterial Hypertension: A Systematic Review and Network Meta-Analysis
Authors:Snigdha Jain  Rohan Khera  Saket Girotra  David Badesch  Zhen Wang  Mohammad Hassan Murad  Amy Blevins  Gregory A. Schmidt  Siddharth Singh  Alicia K. Gerke
Affiliation:1. Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX;2. Division of Cardiology, University of Texas Southwestern Medical Center, Dallas, TX;3. Division of Cardiology, University of Iowa Carver College of Medicine, Iowa City, IA;4. Hardin Library for the Health Sciences, University of Iowa Carver College of Medicine, Iowa City, IA;5. Division of Pulmonary, Critical Care, and Occupational Medicine, University of Iowa Carver College of Medicine, Iowa City, IA;6. Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO;7. Knowledge and Evaluation Research Unit and the Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN;8. Division of Biomedical Informatics, Department of Internal Medicine, University of California San Diego, La Jolla, CA
Abstract:
Keywords:comparative efficacy  network meta-analysis  pulmonary arterial hypertension  6MWD  6-min walk distance  ERA  endothelin receptor antagonist  FDA  Food and Drug Administration  GRADE  Grading of Recommendations Assessment, Development, and Education  NYHA  New York Heart Association  PAH  pulmonary arterial hypertension  PDE5i  phosphodiesterase-5 inhibitor  RCT  randomized controlled trial  RR  risk ratio  SUCRA  surface under the cumulative ranking area  WHO  World Health Organization  WMD  weighted mean difference
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