盐酸米诺环素软膏治疗慢性牙周炎的临床研究

目的 观察盐酸米诺环素软膏治疗慢性牙周炎的临床效果.方法 将40名慢性牙周炎患者100颗患牙随机分成加用碘甘油的对照组和加用盐酸米诺环素软膏的观察组,记录治疗前后的牙周深度、菌斑指数、牙齿松动度、牙周附着水平、龈沟出血指数的改变并进行分析.结果 两组治疗前差异无统计学意义（P〉0.05）,治疗后各时段差异均有统计学意义（均P〈0.05）.结论 盐酸米诺环素软膏的治疗效果优于传统碘甘油治疗方法,能显著提高慢性牙周炎的治疗效果.

Clinical study on hydrochloride minocycline ointment in the treatment of chronic periodontitis

Objective To observe the clinical efficacy of hydrochloride minocycline ointment in the treatment of chronic periodontitis. Methods 40 patients( 100 teeth) with chronic periodontitis were divided into iodine glycerin group (control group)and hydrochloride minocycline ointment group (observation group). Before and after treatment, the changes of the periodontal depth, plaque index, tooth mobility, tooth week attachment level, gingival sulcus bleeding index were recorded and analyzed. Results There was no significant difference between the two groups before treatment (P > 0.05 ), and after treatment, the difference in every excerpt -time was significant (all P <0.05). Conclusion The treatment of hydrochloride minocycline ointment in chronic periodontitis was better than iodine glycerin, and could significantly improve the efficacy.