电休克治疗对抑郁症的疗效研究

目的:评价无抽搐电休克治疗与传统电休克治疗抑郁症的疗效及不良反应.方法:80例抑郁症患者随机分成两组,分别实施无抽搐电休克治疗与传统电休克治疗,采用汉密尔顿抑郁量表(HAMD)、韦氏记忆量表(WMS)及自制不良反应观察表分别评定两组的疗效及不良反应.结果:无抽搐电休克治疗与传统电休克治疗总体疗效相当,但传统电休克治疗起效更快.二者对记忆均有影响,前者对记忆的影响在1～2周内恢复,后者持续2周以上.其他不良反应均较小.结论:无抽搐电休克治疗是一种值得推广的安全有效的治疗抑郁症方法,而传统电休克治疗起效更快,对有高度自杀风险的抑郁症患者的治疗效率可能更高.

Study of efficacy of electric shock therapy in treatment of depression

Objective:To compare the efficacy and side effects between modified-ECT (MECT) and traditional-ECT (TECT) in the treatment of depression. Method:80 inpatients with depression were randomly assigned into MECT group and TECT group.The effects and side reactions were evaluated with Hamilton depression scale (HAMD),Wechsler memory scale (WMS) and self-edit side reactions observation scale before and after the treatment. R esults:Findings indicated that efficacy of MECT was similar to that of T ECT, however TECT took effect more quickly. Both methods have little side effect except for the effect on memory, the period of recovering the memory in MECT gr oup was about 1-2 weeks, but in TECT group more than 2 weeks. Conclusio n:MECT is effective and safe in the treatment of depression,it is valuab le to be recommended clinically.But TECT may be more quickly in the treatment of depression patients who have high risk of suicide.