| 复发性口疮患者细胞免疫功能的研究 |
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| 引用本文： | 石晶,季旭东,曲旭红,韩冰,石爱梅. 复发性口疮患者细胞免疫功能的研究[J]. 医药论坛杂志, 2003, 24(24): 16-17 |
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| 作者姓名： | 石晶 季旭东 曲旭红 韩冰 石爱梅 |
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| 作者单位： | 郑州大学第一附属医院口腔科,郑州市,450052;郑州大学第一附属医院口腔科,郑州市,450052;郑州大学第一附属医院口腔科,郑州市,450052;郑州大学第一附属医院口腔科,郑州市,450052;郑州大学第一附属医院口腔科,郑州市,450052 |
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| 摘 要： | 目的 探讨复发性口疮(recurrent aphthous ulcer,RAU)的发生与细胞免疫之间的关系,为RAU的免疫制剂治疗提供理论依据。方法 选择45例临床确诊为RAU的患者,用间接免疫荧光法检测患者发作期外周血中T淋巴细胞亚群。结果 RAU实验组患者CD3细胞、CD4细胞、CD4／CD8的比值均下降,CD8细胞明显升高,且与正常对照组有明显差异。结论 RAU患者在发作期的细胞免疫功能处于低下状态,提示在治疗中应给予一定的免疫增强剂。
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| 关 键 词： | 复发性口疮 T淋巴细胞亚群 间接免疫荧光法 |
| 修稿时间： | 2003-09-30 |
Study on Cellular Immunity of Recurrent Aphthous Ulcer |
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| Shi Jing,Ji Xudong,Qu Xuhong,Han Bing,Shi Aimei. Study on Cellular Immunity of Recurrent Aphthous Ulcer[J]. Journal of Medical Forum, 2003, 24(24): 16-17 |
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| Authors: | Shi Jing Ji Xudong Qu Xuhong Han Bing Shi Aimei |
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| Abstract: | Objective This experiment is to study the relationship between the recurrent aphthous ulcer(RAU) and cell-mediated immunity in order to make an theoretical base for the immune therapy for RAU.Methods Indirect immunofluorescence was used to detect T lymphocyte subsets in peripheral blood collected from 45 RAU patients.Results The result showed that CD 3,CD 4 and CD 4/CD 8 decreased remarkably (P<0.05) and CD 8 increased significantly(P<0.05)in RAU patients who was in the period of attack.Conlusion RAU patients' cell immunity function was immunosuppression,so we should use some immunoenhancements for RAU patients. |
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| Keywords: | recurrent aphthous ulcer T-lymphocyte subsets indirect immunofluorescence |
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