纤维支气管镜肺泡灌洗术不同治疗时机对难治性肺炎支原体肺炎治疗效果的影响

目的 探讨不同支气管镜肺泡灌洗术治疗时机对难治性肺炎支原体肺炎(RMPP)患儿疗效的影响.方法 选取2015年1月至2016年4月期间我院儿科收治的42例RMPP患儿为研究对象,根据纤维支气管镜肺泡灌洗术治疗时机不同,将术前病程<10 d者纳入早期组(n=22),术前病程≥10 d者纳入晚期组(n=20),比较两组患儿的临床疗效.结果 早期组患儿发热时间、住院时间及影像检查好转时间分别为(12.4±2.5)d、(14.5±1.8)d、(13.1±2.2)d,均明显短于晚期组的(14.5±2.6)d、(16.2±2.1)d、(15.4±2.7)d,差异均有统计学意义(P<0.05);术后1个月复查CT提示早期组患儿完全吸收率为59.09%,明显高于晚期组的30.00%,差异有统计学意义(P<0.05).结论 早期应用纤维支气管肺泡灌洗术治疗可促进难治性肺炎支原体肺炎患儿临床症状及影像学检查的好转,改善患儿的近期预后.

Effect of different treatment timing of bronchoalveolar lavage on treatment effect of children with refractory mycoplasma pneumoniae pneumonia

Objective To investigate the effect of different treatment timing of bronchoalveolar lavage on treat-ment effect of children with refractory mycoplasma pneumoniae pneumonia (RMPP). Methods Forty-two children with RMPP who treated in Department of Pediatrics in our hospital from January 2015 to April 2016 were selected as the research subjects. They were divided into the early group (n=22) with preoperative duration<10 days and late group (n=20) with preoperative duration≥10 days according to the different treatment timing of bronchoalveolar lavage. The clini-cal efficacy were compared between the two groups. Results The fever time, hospitalization time and imaging im-proved time in early group were (12.4 ± 2.5) d, (14.5 ± 1.8) d, (13.1 ± 2.2) d respectively, which were significantly shorter than those in late group of (14.5±2.6) d, (16.2±2.1) d, (15.4±2.7) d, and the differences were statistically significant (P<0.05). At postoperative 1 month, the complete absorption rate by CT was 59.09%in early group, which was significantly higher than that in late group of 30.00%, and the difference was statistically significant (P<0.05). Conclusion Early ap-plication of bronchoalveolar lavage can promote the improvement of clinical symptoms and imaging examination in chil-dren with RMPP, and improve the short-term prognosis.