| 愈伤灵膏的抗炎镇痛作用 |
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| 引用本文： | 李艳春,马恩龙,甘乐凌,王敏伟.愈伤灵膏的抗炎镇痛作用[J].沈阳药科大学学报,2004,21(6):454-457. |
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| 作者姓名： | 李艳春 马恩龙 甘乐凌 王敏伟 |
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| 作者单位： | 沈阳药科大学,药学院,辽宁,沈阳,110016 |
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| 基金项目： | 辽宁省科学技术计划项目 (982 2 6 0 0 3) |
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| 摘 要： | 目的研究愈伤灵膏的抗炎镇痛作用。方法采用血管通透性实验、小鼠耳肿胀实验、大鼠角叉菜胶性足跖肿胀实验、小鼠光热法及醋酸所致小鼠扭体反应等炎症、疼痛模型考察愈伤灵膏的抗炎镇痛作用。结果愈伤灵膏可明显抑制烫伤部位毛细血管通透性 ;对角叉菜胶致大鼠足肿胀和二甲苯致小鼠耳肿胀有明显的抑制作用 ;对光热致小鼠足部疼痛、醋酸致小鼠扭体均有明显的镇痛效果。结论愈伤灵膏具有明显的抗炎、镇痛药效
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| 关 键 词： | 镇痛 抗炎 愈伤灵膏 |
| 文章编号： | 1006-2858(2004)06-0454-04 |
| 修稿时间： | 2003年11月18 |
Anti-inflammatory and analgesic effect of the Yushangling Ointment |
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| LI Yan-chun,MA En-long,GAN Le-ling,WANG Min-wei.Anti-inflammatory and analgesic effect of the Yushangling Ointment[J].Journal of Shenyang Pharmaceutical University,2004,21(6):454-457. |
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| Authors: | LI Yan-chun MA En-long GAN Le-ling WANG Min-wei |
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| Abstract: | Objective To study anti-inflammatory and analgesic effect of the Yushangling Ointment.Methods Different pain and inflammatory models were made to investigate the anti-inflammatory and analgesic effects of the Yushangling Ointment.Results The results of the anti-inflammatory experiments showed that ear edema resulted from dimethyl benzene and paw edema induced by carragheenin were significantly inhibited by the Yushangling Ointment; permeability of micro-vessels of post-burned wound in rats and mice was greatly decreased.And the Yushangling Ointment also produced obvious analgesic effects on the pain model of body-twisting caused by acetic stimulus in mice and light-heat stimulation in mice.Conclusion The Yushangling Ointment has significant anti-inflammatory and analgesic effect. |
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| Keywords: | analgesic effect anti-inflammatory effect Yushangling Ointment |
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