广州地区中老年腰椎骨密度定量CT（QCT）测量分析

目的探讨64层螺旋CT定量测量（QCT）广州地区中老年患者腰1～腰5椎体骨密度差异及其一临床价值。方法随机选取年龄36—85岁患者140例，男75名、女65名，按10岁1个年龄段分组，应用东芝64层螺旋CT配套体模及应用软件进行腰椎骨密度定量测量，比较腰1～腰5椎体骨密度随年龄增长的变化及其差异。结果中老年患者腰1-腰5椎体骨密度定量值随年龄增长而逐渐降低，而56～65岁年龄段骨量下降明显加速（P〈0．01）。女性骨密度值峰值高于男性，而随年龄增长其值下降比较迅速，46—55岁以后骨密度明显低于男性。结论本研究探索了广州地区中老年人腰椎骨质密度的变化特征，其在QCT骨密度测量和骨质疏松诊断中有着重要作用。

Measurement of Lumbar BMD with QCT in Middleaged or Elderly Individuals Licing in Guangzhou Area

Objective To explore the lumbar bone mineral density(BMD) differences and their clinical value among the middle-aged or elderly individuals living in Guang Zhou aera with quantitative CT(QCT).Materials and methods The BMD in ecvery vertebra of lumbar spine was ince stigated by QCT(Toshiba’s 64-slice CT) in 140 patients(75 male,65 female) age from 36 to 85 years.They were divided into groups every ten years.Result The BMD in vertebra of lumbar spine(L1～L5) BMD declined with aging.The BMD was predominantly declined in group of 56 to 65 years(p<0.01).The PBM(peak bone density) of female is higher than male,but the BMD of female declined more quickly,lower than the BMD of male after 46-55 years old.Conclusions Through the investigation,the middleaged or elderly individuals’s change pattem of BMD in Guang Zhou area are obtained,it has an important effect in diagnosing osteoporosis with QCT.