| 慢性阻塞性肺病、慢性肺原性心脏病患者白细胞粘附功能的研究 |
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| 引用本文： | 陈宇洁,彭香,陆海英,赵杰,万晓兵,雷松,周东. 慢性阻塞性肺病、慢性肺原性心脏病患者白细胞粘附功能的研究[J]. 华西医学, 2001, 16(1): 105-106 |
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| 作者姓名： | 陈宇洁 彭香 陆海英 赵杰 万晓兵 雷松 周东 |
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| 作者单位： | 1. 四川省第四人民医院,
2. 华西医科大学附属第一医院 |
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| 基金项目： | 四川省科委重点科学技术研究基金资助项目!(97- 0 1 4 ) |
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| 摘 要： | 目的 :探讨慢阻肺、肺心病患者白细胞与正常内皮细胞粘附特点。方法 :采用流室系统对正常人、慢阻肺、肺心病患者血白细胞与正常内皮细胞粘附特性进行研究。结果 :慢阻肺及肺心病患者组血白细胞粘附率较正常组明显增强 (P <0 0 5 ) ;肺心病组的白细胞粘附率较慢阻肺组亦有显著性增强 (P <0 0 5 )。结论 :白细胞粘附作用的增强在慢阻肺、肺心病的发病过程中起了重要作用。
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| 关 键 词： | 慢性阻塞性肺病 慢性肺原性心脏病 白细胞粘附 内皮细胞粘附 |
| 文章编号： | 1002-0179(2001)01-0105-02 |
| 修稿时间： | 2000-10-22 |
Study the Function of Leukocyte Adhesion in the COPD and the Chronic Cor Pulmonale |
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| CHENG Yu jie,PENG Xiang,LU Hai ying,et al.. Study the Function of Leukocyte Adhesion in the COPD and the Chronic Cor Pulmonale[J]. West China Medical Journal, 2001, 16(1): 105-106 |
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| Authors: | CHENG Yu jie PENG Xiang LU Hai ying et al. |
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| Affiliation: | CHENG Yu jie,PENG Xiang,LU Hai ying,et al. |
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| Abstract: | Objective:Study the adhesion characters between the leukocytes and the normal endothelium cells in the COPD and the Cor pulmonale patients.Methods:By flow chamber system,study the adhesion characters between the leukocytes and the normal endothelium cells respectively in normal,COPD and Cor pulmonale patients.Results:Leukocytes adhesion rates are significantly increased in the COPD group and the Cor pulmonale group than the normal one( P <0 05),and leukocyte adhesion rate in the Cor pulmonale group is much higher than the COPD group ( P <0 05).Conclusion:Increase of the adhesion between the leukocytes plays an important role in the pathogenesis of COPD and of Cor pulmonale. |
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| Keywords: | chronic obstructive pulmonary(COPD) chronic Cor pulmonale adhesion leukocyte endothelium cell |
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