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糖皮质激素在风湿病治疗中的应用及其并发症的处理
引用本文:薛愉,万伟国. 糖皮质激素在风湿病治疗中的应用及其并发症的处理[J]. 上海医药, 2012, 0(19): 25-31
作者姓名:薛愉  万伟国
作者单位:复旦大学附属华山医院风湿科 上海 200040
摘    要:
糖皮质激素是凤湿病治疗中的最重要药物,具有强力的免疫抑制和抗炎作用,但在改变病理过程的同时也会打破原有的生理平衡,导致并发症的发生。因此,准确认识、规范应用和及时防治糖皮质激素的并发症对临床医师来说十分重要。本文就糖皮质激素的生理作用、药理机制以及规范化应用和并发症防治进行概述。

关 键 词:糖皮质激素  生理作用  药理机制  风湿病  不良反应

Application of glucocorticoid in the treatment of rheumatic diseases and the prevention and treatment of its complication
XUE Yu, WAN Wei-guo. Application of glucocorticoid in the treatment of rheumatic diseases and the prevention and treatment of its complication[J]. Shanghai Medical & Pharmaceutical Journal, 2012, 0(19): 25-31
Authors:XUE Yu   WAN Wei-guo
Affiliation:(Division of Rheumatology, Huashan Hospital, Fudan University, Shanghai 200040, China)
Abstract:
Glucocorticoid is the most important and widely used drug in treatment of rheumatic diseases, which has powerful immunosuppressive and anti-inflammatory effects. But when altering the pathological process, it will break the original physiological balance resulting in the occurrence of complication. Therefore, it is very important for the clinical physicians to accurately understand, standardize the application and timely prevent and treat the complication of the glucocorticoid. In this article, we introduce the physiological role, pharmacological mechanism, standardizational use and prevention and treatment of the complication.
Keywords:glucocorticoid  physiological role  pharmacological mechanism  rheumatic disease  side-effect
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