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Synthesis of new diselenide compounds as anti-inflammatory agents
Authors:Liulan?Shen,Kyung-Min?Shin,Kyung-Tae?Lee,Jin-Hyun?Jeong  mailto:jeongjh@khu.ac.kr"   title="  jeongjh@khu.ac.kr"   itemprop="  email"   data-track="  click"   data-track-action="  Email author"   data-track-label="  "  >Email author
Affiliation:College of Pharmacy, Kyung Hee University, Seoul 130-701, Korea.
Abstract:
Many diselenide compounds are used as antioxidants, enzyme inhibitors and cytokine inducers. Three new diselenide compounds, bis-(2-hydroxyphenyl) diselenide, bis-(3-hydroxyphenyl) diselenide and bis-(4-hydroxyphenyl) diselenide were designed and synthesized as anti-inflammatory agent. All of them were found to have strong in vitro activity in anti-inflammatory assays.
Keywords:Organoselenium compound  Bis-(hydroxyphenyl) diselenide  Diselenide  Antiinflammatory activity
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