宫颈癌细胞信号通路的研究进展

人类乳头瘤病毒(HPV)是宫颈癌的主要致病因子,细胞信号通路的异常往往影响细胞增殖和分化的正常调控,导致癌的发生。因此可以把信号途径作为宫颈癌治疗的重要靶点,通过对细胞信号途径的干预调整靶基因表达,使其恢复正常,以达到抑制肿瘤生长、治疗肿瘤的目的。现就HPV、宫颈癌与信号通路三者的相关性研究进行综述。

A Study on Cell Signaling Pathway in Cervical Cancer

Human papillomavirus(HPV)is the major pathogenic factor of cervical cancer,and abnormal cell signaling pathway often affects cell proliferation and differentiation of normal regulation,leading to cancer.Therefore,signaling pathway can be an important target for cancer treatment,through the intervention of which to adjust the target gene expression to normal,in order to achieve inhibition of tumor growth and treatment of the primary tumor.Here is to make a review on the research of the correlation between HPV,cervical cancer and recognized signaling pathway.