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| 药物后处理对心肌保护作用机制的研究进展 | |
| 引用本文： | 郭家龙. 药物后处理对心肌保护作用机制的研究进展[J]. 医学综述, 2012, 18(13): 2043-2045 |
| 作者姓名： | 郭家龙 |
| 作者单位： | 湖北医药学院附属太和医院心胸外科,湖北,十堰,442000 |
| 摘 要： | 缺血后处理是在心肌遭受致命性的再灌注损伤的初始阶段,所给予的一种可控的、短暂的、反复间断的缺血/再灌注处理,这样可以明显减轻心肌的缺血/再灌注损伤。近年来,人们又日益深入地研究一种新的心肌保护策略:药物后处理。现对药物后处理对缺血/再灌注心肌保护作用机制的研究进展进行综述。 |
| 关 键 词： | 药物后处理 心肌保护 缺血/再灌注损伤 信号通路 线粒体通透性转换孔 |
Research Progress of the Mechanism of Myocardium Protection by Pharmacological Postconditioning |
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| GUO Jia-long. Research Progress of the Mechanism of Myocardium Protection by Pharmacological Postconditioning[J]. Medical Recapitulate, 2012, 18(13): 2043-2045 | |
| Authors: | GUO Jia-long |
| Affiliation: | .(Department of Cardiothoracic Surgery,Taihe Hospital Affiliated to Hubei University of Medicine,Shiyan 442000,China) |
| Abstract: | Postconditioning is an intervention of controlled,brief intermittent ischaemia-reperfusion treatment at the onset of fatal reperfusion injury of myocardium to relieve injury.In recent years a new myocardium protection strategy has been explored:pharmacological postconditioning.Here is to make a review on the research progress of the mechanism. |
| Keywords: | Pharmacological postconditioning Myocardium protection Ischaemia-reperfusion injury Signal pathway Mitochondrial permeability transition pore |
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