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| 桃红四物汤对痛经模型小鼠干预作用的研究 | |
| 引用本文： | 李鹏,李祥,陈建伟. 桃红四物汤对痛经模型小鼠干预作用的研究[J]. 现代中药研究与实践, 2010, 0(4): 37-39 |
| 作者姓名： | 李鹏 李祥 陈建伟 |
| 作者单位： | [1]南京中医药大学药学院,江苏南京210046 [2]江苏省方剂研究重点实验室,江苏南京210046 |
| 基金项目： | 江苏省方剂研究重点实验室开放课题（022021014004）; 江苏省高校自然科学重大基础研究项目（NO.06K.JA.36022） |
| 摘 要： | 目的探讨桃红四物汤对痛经模型小鼠的干预作用。方法采用乙烯雌酚结合缩宫素致小鼠痛经模型对桃红四物汤各提取部位进行药效筛选。将药效显著部位进行量效关系研究。结果桃红四物汤醇提部位以及醇提物中的石油醚部位对痛经模型小鼠有明显的延长潜伏期及抑制疼痛作用。结论石油醚部位是桃红四物汤抑制痛经模型小鼠的药效显著部位。 |
| 关 键 词： | 桃红四物汤 痛经 量效关系 |
Study on Effects for Intervention Dysmenorrheal of Taohong Siwu Decoction in Model Mice |
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| LI Peng,LI Xiang,CHEN Jian-wei. Study on Effects for Intervention Dysmenorrheal of Taohong Siwu Decoction in Model Mice[J]. Research and Practice on Chinese Medicines, 2010, 0(4): 37-39 | |
| Authors: | LI Peng LI Xiang CHEN Jian-wei |
| Affiliation: | 1.Nanjing University of Chinese Medicine,Nanjing 210046,China;2.Jiangsu Key Laboratory for TCM Formulae Research,Nanjing 210046,China) |
| Abstract: | Objective To study the active part of Taohong Siwu Decoction （THSWD） for intervention dysmenorrheal effect in model mice.Methods Screening the effective extracted parts from THSWD in dysmenorrheal mice mode which induced by estradiol and oxytocin.Then investigate the dose-effect relationship of the active part.Results The length of latent period and analgesic effect of ethanol suspension and subdivision sites of ethanol suspension from THSWT are different from that of blank control.The petroleum ether extracts is one of the most effective parts.Conclusion The lip soluble component from THSWD is the active part. |
| Keywords: | Taohong Siwu Decoction dysmenorrheal model dose-effect relationship |
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