加味洗心汤合多奈哌齐治疗老年性痴呆的临床研究

目的：观察加味洗心汤合多奈哌齐治疗老年性痴呆的疗效。方法：将126例患者随机分成两组，治疗组63例用加味洗心汤合多奈哌齐口服；对照组用尼莫地平、茴拉西坦、多奈哌齐口服。两组均治疗3个疗程，治疗前后测定精神状态评分量表（MMSE），长谷川简易智能修订量表（HDS-R），日常生活能力量表（ADL）评分值。结果：治疗组总有效率95.2%，对照组总有效率77.8%，MMSE、HDS-R、ADL评分改善，治疗组优于对照组，统计学具有差异（P<0.05）。结论：加味洗心汤合多奈哌齐治疗老年性痴呆疗效显著，具有补骨填精，益气安神，化痰醒脑的功效，明显优于对照组。

Clinical research on treating senile dementia with the Xixin decoction plus the donepezil

Objective： To observe the effect of the Xixin decoction plus the donepezil on treating senile dementia. Methods： 126 cases were randomly divided into the treatment group and the control group. 63 cases of the treatment group were given the Xixin decoction plus oral donepezil, while the control group was given oral nimodipine, aniracetam and the donepezil. The treatment of each group lasts 3course. To measure scores of the MMSE, the HDS-R and the ADL. Results： The total efficiency of the treatment group was 95.2%, while the control group was 77.8%. The scores of the MMSE, the HDS-R and the ADL improved. The treatment group was better. The differences were statistically significant. Conclusion： The effect of the Xixin decoction plus the donepezil was significant and better than the control group.