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Transient blood plasmacytosis in parvovirus B19 infection: a report of two cases
Authors:P. R. Koduri  S. J. Naides
Affiliation:(1) Department of Medicine Division of Hematology, Room 811 Cook County Hospital 627 S. Wood, 60612 Chicago, IL, USA;(2) Department of Internal Medicine Division of Rheumatology, University of Iowa College of Medicine, 52242 Iowa City, IA, USA;(3) The Veterans Affairs Medical Center, 52240 Iowa City, IA, USA
Abstract:
Two patients with sickle cell disease were diagnosed with aplastic crisis caused by acute parvovirus B19 infection. One patient also developed thrombocytopenia associated with hemophagocytic histiocytosis in the bone marrow biopsy. Both patients developed transient blood plasmacytosis and hypocomplementemia soon after admission to the hospital. Transient blood plasmacytosis may be an immunological response to acute parvovirus B19 infection.
Keywords:Parvovirus B19  Histiocytosis  Non-Langerhans cell  Plasma cells  Sickle cell disease  Thrombocytopenia
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