社区综合性干预对慢性阻塞性肺疾病患者肺功能和生活质量的影响

目的　评价社区综合干预治疗慢性阻塞性肺疾病 (chronicobstructivepulmonarydisease,COPD)的效果。方法　选取华中科技大学 2 3名COPD患者为干预组 ,进行戒烟、COPD防治知识、康复治疗及氧疗等教育 ,并定期进行咨询和指导性治疗 ,包括雾化吸入支气管扩张剂 ,应用祛痰药和茶碱缓释片 ;2 2名未参与社区综合干预治疗的COPD患者作为对照组。 2组患者均具有较高学历。观察 2年后 ,分别采用肺功能和生活质量 (qualityoflife,QOL)评分进行评估。结果　 2年后 ,干预组与对照组比较 ,一秒用力呼气容积(FEV1 )与用力肺活量 (FVC)平均每年的下降速度差异有显著性 ,在COPDI、II级患者中尤为明显 ;干预组QOL评分低于对照组 ,2组比较 ,差异有显著性意义 (P <0 .0 5)。结论　社区综合性干预治疗COPD ,能有效改善患者肺功能及生活质量 ;患者的文化素质对病情无明显影响

The effect of community comprehensive medical interventions on the pulmonary function and quality of life in patients with chronic obstructive pulmonary diseases

Objective To evaluate the effect of community medical intervention on pulmonary function and quality of life (QOL) in the patients suffering from the chronic obstructive pulmonary disease(COPD). Methods Forty five COPD patients in Huazhong University of Science and Technology were recruited and divided into an intervention group( n =23) and a control group( n =22). For those in the intervention group, a series of medical programs were performed during a two year period, including propaganda of quitting smoke, COPD exacerbation prevention approaches, hygienical instruction and rehabilitative exercise. Those in the control were not given the above interventions. Then the pulmonary function and QOL of COPD patients in the two groups were retrospectively analyzed. Results Two years later, significant difference was revealed between the two groups in regard to the average annual decrease rates of FEV 1 and FVC, while the difference in annual decrement of FEV 1 % and FVC% was more remarkable in those with grades I and II COPD in the two groups. QOL was significantly improved in the intervention group as compared with those in the control group. Conclusion Comprehensive community interventions for COPD can improve patients' pulmonary function and their QOL.