|
|||||
|
|
| 注射用还原型谷胱甘肽与肌苷葡萄糖注射液配伍稳定性考察 | |
| 引用本文： | 李湘晖,田甜,杜智敏. 注射用还原型谷胱甘肽与肌苷葡萄糖注射液配伍稳定性考察[J]. 中国药师, 2010, 13(8): 1149-1150 |
| 作者姓名： | 李湘晖 田甜 杜智敏 |
| 作者单位： | [1]哈尔滨医科大学附属二院药学部,哈尔滨150086 [2]黑龙江省普通高校药物研究重点实验室,哈尔滨150086 |
| 摘 要： | 目的：考察注射用还原型谷胱甘肽和肌苷葡萄糖注射液的配伍稳定性。方法：采用紫外分光光度法，测定室温（25℃）条件下6h内配伍液中2组分的含量变化，并比较配伍前后外观、pH的变化。结果：配伍6h内肌苷含量无明显变化。还原型谷胱甘肽的含量却下降至原来的41．1％。其余考察指标无显著性变化。结论：注射用还原型谷胱甘肽与肌苷葡萄糖注射液可以配伍使用，但应在2h内用完。 |
| 关 键 词： | 还原型谷胱甘肽 肌苷 配伍稳定性 紫外分光光度法 |
Study on Compatibility Stability of Reduced Glutathione Injection with Inosine Glucose Injection |
|
| Li Xianghui,Tian Tian,Du Zhimin. Study on Compatibility Stability of Reduced Glutathione Injection with Inosine Glucose Injection[J]. China Pharmacist, 2010, 13(8): 1149-1150 | |
| Authors: | Li Xianghui Tian Tian Du Zhimin |
| Affiliation: | 1. Pharmacy Department, the 2nd Affiliated Hospital of Harbin Medical University, Heilongjiang, Harbin 150086, China;2. Key Laboratory of Drugs Research, College of Heilongjiang Province) |
| Abstract: | Objective： To study the compatibility of reduced glutathione for injection and inosine glucose injection. Method： The contents of 2 constituents of the mixed solution stored at 25 ℃ within 6 hours was determined by ultraviolet wavelength spectrophotometry, and the appearance, pH value of the mixture were compared with those before. Result： There was no significant change in the content of inosine after mixing for 6 h ,while the content of reduced glutathione down to the original 41.1% at 6 h, no significant changes were noted otherwise. Conclusion： Reduced glutathione for injection is compatible with Inosine glucose injection if at 25℃ within 2 hours＇ mixing. |
| Keywords: | Reduced glutathione Inosine Compatibility stability UV |
| 本文献已被 维普 万方数据 等数据库收录！ | |