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Hydroxychloroquine‐induced hyperpigmentation: a case report
Authors:M. A. Melikoglu MD  M. Melikoglu MD  U. Gurbuz MD  B. S. Budak MD  C. Kacar MD
Affiliation:1. Department of Rheumatology, Physical Medicine and Rehabilitation, School of Medicine, Akdeniz University, Antalya;2. Department of Physical Medicine and Rehabilitation, School of Medicine, Ataturk University, Erzurum;3. Department of Dermatology, School of Medicine, Ataturk University, Erzurum;4. Department of Physical Medicine and Rehabilitation, School of Medicine, Akdeniz University, Antalya, Turkey
Abstract:
The antimalarials are one of the most commonly prescribed drugs in medical practice, for conditions such as rheumatoid arthritis as well as malaria. They are generally well‐tolerated and the possible side effects of synthetic antimalarials, though infrequent, are well known. Besides the familiar adverse reactions, a localized mucocutaneous bluish‐grey to black discolouration can sometimes be seen with antimalarial drugs. The aim of this report was to draw attention to the localized mucocutaneous bluish‐grey hyperpigmentation induced by hydroxychloroquine with a case presentation and a review of the literature.
Keywords:antimalarials  hydroxychloroquine  hyperpigmentation
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