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Role of propolis on biochemical parameters in kidney and heart tissues against l-NAME induced oxidative injury in rats
Authors:Zeliha Selamoglu Talas  Ilknur Ozdemir  Osman Ciftci  Oguz Cakir  Mehmet Fuat Gulhan  Oguz Murat Pasaoglu
Affiliation:1. Department of Biology, Faculty of Arts and Sciences, Nigde UniversityNigdeTurkey;2. Department of Chemistry, Faculty of Arts and Sciences, Inonu UniversityMalatyaTurkey;3. Department of Pharmacy Faculty, Inonu UniversityMalatyaTurkey;4. Department of Science and Technology Research Application Center Dicle UniversityDiyarbakirTurkey
Abstract:
Nitric oxide (NO), produced by endothelial NO synthase, is recognised as a central antiinflammatory and antiatherogenic principle in the vasculature. Epidemiological and clinical studies have demonstrated that a growing list of natural products, as components of the daily diet or phytomedical preparations, may improve vascular function by enhancing NO bioavailability. In this article, we investigated antioxidant effects of propolis on biochemical parameters in kidney and heart tissues of acute NO synthase inhibited rats by Nω-nitro-l-arginine methyl ester (l-NAME). There was increase (p?p?
Keywords:Catalase  l-NAME  malondialdehyde  nitric oxide  propolis  rat
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