Significant benefits after renal transplantation in patients with chronic heart failure and chronic kidney disease |
| |
| Authors: | Vivek B. Kute Aruna V. Vanikar Himanshu V. Patel Manoj R. Gumber Pankaj R. Shah Divyesh P. Engineer |
| |
| Affiliation: | 1. Department of Nephrology and Clinical Transplantation, Institute of Kidney Diseases and Research Center, Dr. HL Trivedi Institute of Transplantation Sciences, (IKDRC-ITS)AhmedabadIndia;2. Department of Pathology, Laboratory Medicine, Transfusion Services and Immunohematology |
| |
| Abstract: | Background: Chronic heart failure (CHF) and chronic kidney disease (CKD) are serious medical conditions with significant morbidity and mortality and often coexist. Because of perioperative risks in these patients, they may not be considered a candidate for renal transplantation (RTx).Material and methods: We compare retrospectively RTx outcomes [graft/patient survival, rejection rates and adverse cardiac events] in study group [low left ventricular ejection fraction (LVEF) ≤45% by echocardiogram, n?=?63] and control group [normal LVEF ≥50%, n?=?537] from a developing country.Results: The mean EF was 35?±?5.6 and 57?±?3% for the study and control groups, respectively (p?Conclusion: RTx may play a role in reversing LV systolic dysfunction. Once thought by many to be a contraindication for renal transplantation, this appears not to be the case. The outcomes between the 2 groups are comparable and transplant is an option for even low EF patients. |
| |
| Keywords: | Chronic heart failure chronic kidney disease low ejection fraction outcome renal transplantation |
|
|
