The effect of ginger consumption on glycemic status,lipid profile and some inflammatory markers in patients with type 2 diabetes mellitus |
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Authors: | Tahereh Arablou Majid Valizadeh Faranak Sharifi AghaFatemeh Hosseini Mahmoud Djalali |
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Affiliation: | 1. Department of Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical SciencesTehranIran;2. Zanjan Metabolic Disease Research Center, Zanjan University of Medical SciencesZanjanIran;3. Department of Statistics and Mathematics, School of Health Management and Information Science, Iran University of Medical SciencesTehranIran;4. Department of Nutrition and Biochemistry, School of Nutritional Sciences and Dietetics, Tehran University of Medical SciencesTehranIran |
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Abstract: | Objective: To assess the effect of ginger consumption on glycemic status, lipid profile and some inflammatory markers in patients with type 2 diabetes mellitus. Methods: In a double-blinded, placebo-controlled clinical trial, 70 type 2 diabetic patients were enrolled. They allocated randomly into ginger group and control group. They consumed 1600?mg ginger versus 1600?mg wheat flour placebo daily for 12 weeks. Serum sugar, lipids, CRP, PGE2 and TNFα were measured before and after intervention. Results: Ginger reduced fasting plasma glucose, HbA1C, insulin, HOMA, triglyceride, total cholesterol, CRP and PGE2 significantly compared with placebo group (p?0.05). There were no significant differences in HDL, LDL and TNFα between two groups (p?>?0.05). Conclusion: Ginger improved insulin sensitivity and some fractions of lipid profile, and reduced CRP and PGE2 in type 2 diabetic patients. Therefore ginger can be considered as an effective treatment for prevention of diabetes complications. |
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Keywords: | Blood sugar ginger inflammation insulin sensitivity serum lipids type 2 diabetes |
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