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The Clinical Spectrum of Myocardial Infarction and Ischemia With Nonobstructive Coronary Arteries in Women |
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| Authors: | Inge J van den Hoogen Umberto Gianni Malissa J Wood Viviany R Taqueti Fay Y Lin Sharonne N Hayes Gudrun M Feuchtner Alexander R van Rosendael Nanette K Wenger Janet Wei C Noel Bairey Merz Carl J Pepine Leslee J Shaw |
| Institution: | 1. Dalio Institute of Cardiovascular Imaging, Department of Radiology, NewYork-Presbyterian Hospital and Weill Cornell Medical College, New York, New York, USA;2. Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands, USA;3. Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA;4. Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA;5. Department of Radiology, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA;6. Women’s Heart Clinic, Mayo Clinic, Rochester, Minnesota, USA;7. Department of Radiology, Medical University of Innsbruck, Innsbruck, Austria;8. Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia, USA;9. Barbara Streisand Women''s Heart Center, Cedars-Sinai Medical Center, Los Angeles, California, USA;10. Division of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, Florida, USA |
| Abstract: | Women exhibit less burden of anatomic obstructive coronary atherosclerotic disease as compared with men of the same age, but contradictorily show similar or higher cardiovascular mortality rates. The higher prevalence of nonexertional cardiac symptoms and nonobstructive coronary atherosclerotic disease in women may lead to lack of recognition and appropriate management, resulting in undertesting and undertreatment. Leaders in women’s health from the American College of Cardiology’s Cardiovascular Disease in Women Committee present novel imaging cases that may provoke thought regarding the broad clinical spectrum of myocardial infarction and ischemia with nonobstructive coronary arteries in women. These unique imaging approaches are based on the concept of targeting sex-specific differences in acute and stable ischemic heart disease. |
| Keywords: | atherosclerosis coronary microvascular dysfunction ischemia and no obstructive coronary arteries INOCA MINOCA myocardial infarction with nonobstructive coronary arteries sex women |
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