| 组织蛋白酶B、L在非小细胞肺癌中的表达及意义 |
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| 引用本文： | 朱丽娟,崔永安. 组织蛋白酶B、L在非小细胞肺癌中的表达及意义[J]. 临床肺科杂志, 2009, 14(10): 1311-1312 |
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| 作者姓名： | 朱丽娟 崔永安 |
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| 作者单位： | 扬州大学医学院第四临床医院,南通瑞慈医院呼吸科,江苏,226010;扬州大学医学院第四临床医院,南通瑞慈医院呼吸科,江苏,226010 |
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| 摘 要： | 目的探讨组织蛋白酶B、L在非小细胞肺癌中的表达及意义。方法收集44例非小细胞肺癌标本,石蜡包埋切片,通过免疫组化的方法检测组织蛋白酶B、L的表达。结果组织蛋白酶B、L随着肿瘤分期的进展其表达阳性率明显升高,Ⅲ期～Ⅳ期的病人组织蛋白酶B、L的表达与I期-Ⅱ期的病人有显著差异（P〈0．05）。组织蛋白酶B和L的表达高度相似。结论组织蛋白酶B、L的表达与非小细胞肺癌的进展和预后有关。
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| 关 键 词： | 组织蛋白酶B 组织蛋白酶L 非小细胞肺癌肺癌 |
Expression and significance of cathepsin B and cathepsin L in non-small cell lung carcinoma |
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| ZHU Li-juan,CUI Yong-an. Expression and significance of cathepsin B and cathepsin L in non-small cell lung carcinoma[J]. Journal of Clinical Pulmonary Medicine, 2009, 14(10): 1311-1312 |
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| Authors: | ZHU Li-juan CUI Yong-an |
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| Affiliation: | ( Respiratory Department ,Rici Hospital of Nantong City, the 4th Hospital for Clinical Medical of Yangzhou Medical University,Jiangsu Province 226010,China) |
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| Abstract: | Objective To discuss the expression and significance of cathepsin B and cathepsin L in non-small cell lung carcinoma. Methods Immunohistechemistry was used to detect CB and CL expression in tissues of 44 non-small cell lung cancinoma patients. ResuhsPositive expression rate of CB and CL was higher in phrases of Ill to IV than in phrases of I to lI. The expression of CB was similar to the expression of CL. Conclusion The expression of CB and CL has correlation with NSCLC metastasis and prognosis. |
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| Keywords: | athepsin B cathepsin L non-small cell lung carcinoma |
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