针药结合治疗类风湿关节炎临床疗效的Meta分析

目的:评价针药结合治疗类风湿关节炎(RA)的有效性。方法:计算机检索PubMed、CBM、CNKI、VIP、万方数据库针药结合治疗RA的随机对照试验,检索时限为2003年1月-2013年6月。由两名研究人员根据纳入及排除标准,独立筛选文献、提取资料、质量评价后,采用RevMan5.1软件进行Meta分析。结果:共纳入19个RCT,Meta分析结果显示:与药物对照组比较,针药结合在总有效率[OR=3.59,95%CI(2.72,4.74),P<0.00001],两组差异具有统计学意义。结论:研究结果表明,与药物治疗相比,针药结合治疗RA的总有效率更高,但受纳入研究质量限制,仍需开展多中心、大样本、高质量的随机对照试验来验证。

Clinical Meta analysis of treating RA in TCM and acupuncture

Objective： To evaluate combined treatment of rheumatoid arthritis （RA）. Methods： A randomized controlled trial, searching PubMed, CBM, CNKI, VIP, WanFangDATA for combined treatment of RA is from January 2003 to June 2013. By two researchers based on inclusion and exclusion criteria, independent screening literature, data extraction, quality assessment were running by RevMan5.1 Meta-analysis software. Results： A total of 19 RCT, Meta analysis showed that： Compared with the control group of drugs, acupuncture and TCM herbs in total efficiency [OR=3.59,95% CI （2.72,4.74）, P＆lt;0.00001], the difference was statistically significance. Conclusion：The results show that compared with medicine therapy, acupuncture combined treatment of RA have higher overall efficiency, but by limiting from the quality of included studies still need to conduct multi-center, large sample, high-quality randomized controlled trials to verify.