空腹血糖及糖化血红蛋白用于筛查糖耐量减退的比较性研究

目的比较空腹血糖（FPG）和糖化血红蛋白（HbAlc）在筛查糖耐量减退（IGT）中的应用价值。方法到我院门诊为明确有无血糖异常而就诊者336人，测定空腹血糖、糖化血红蛋白，并行口服葡萄糖耐量试验（OGTT）。结果按照1999年WHO的DM诊断标准，本研究人群空腹血糖〈6．1者124例，≥6．1-〈7．0者56例，≥7．0者156例；糖化血红蛋白〈6．1者84例，≥6．1者252例；OGTT2 hPG〈7．8者92例，≥7．8-〈11．1者99例，≥11．1者145例。结论糖化血红蛋白和空腹血糖均不适用于筛查IGT人群，但糖化血红蛋白比空腹血糖提示病人是否存在血糖异常更敏感。

The investigation of using fasting plasma glucose and HbA1C for the screening of impaired glucose tolerance

Objective To assess the validity of using fasting plasma glucose(FPG) and HbA1C for the screening of impaired glucose tolerance(IGT).Methods FPG,HbA1C and oral glucose tolerance test(OGTT) were examined by 336 subjects.Results Using 1999 WHO criteria,124 subjects had normal FPG,56 subjects had impaired fasting glucose(IFG),there are 156 subjects whose FPG equal to or above 7.0;There are 84 subjects whose HbA1C less than 6.1 and 252 subjects equal to or above 6.1;92 subjects had normal OGTT 2hPG,99 subjects had IGT,145 subjects had diabetes.Conclusion FPG or HbA1c was not reliable identify IGT,but HbA1c was more sensitive than FPG in detecting abnormal plasma glucose.