功能磁共振成像在脑膜瘤患者运动功能区的应用

目的：探讨血氧水平依赖功能磁共振技术(BOLD-fMRI)在脑膜瘤患者运动功能区术前定位的价值。方法收集10例经术后病理证实的靠近运动区的大脑凸面脑膜瘤患者，采用概率独立成分分析(PICA)，进行 ICA 分析。术前术后行远期生活质量评估(KPS)生活状态评分来评价患者的状态。结果双侧主要运动皮层及辅助运动皮层均出现运动功能激活簇，其中患侧激活区与对侧激活区相比较为对称的有6例，出现明显推压移位的有4例，患者运动功能激活区均被肿瘤挤压导致功能区向前或向后移位，并且出现拉伸变形。结论 BOLD-fMRI 能够有效对脑肿瘤患者进行术前运动功能区定位，对脑膜瘤患者术前手术计划的制定能够提供帮助。

Application study of the motor function area in patients with meningioma by functional magnetic resonance imaging

Objective To evaluate the functional features of motor function area in patients with meningioma by blood oxygenation level dependent functional magnetic resonance imaging (BOLD-fMRI).Methods fMRI were obtained from 10 patients who suffered from meningioma which was adjacent to the motor function cortex.Probabilistic independent component analysis method was used for data analysis.Preoperative and postoperative line Karnofsky Performance Scale (KPS)score was used to assess the patient’s condition.Re-sults Contralateral primary motor cortex and the supplementary motor cortex motor functions were observed in all the activation clusters,in which one side activation area compared with the contralateral activation zone was symmetrical in 6 cases,and significant shift in 4 cases.In 4 patients with the movement function activated,tumor extrusion function shift forward or backwardwith tensile deforma-tion were found.Conclusion BOLD-fMRI imaging technology can effectively locate motor functional area for patients with meningi-oma,which can provide preoperative surgical planning.