右美托咪定辅助用药对全麻苏醒期躁动的影响

目的:观察右美托咪定辅助用药对全麻苏醒期躁动的影响。方法:选择全麻患者60例,按入院时间随机分成右美托咪定辅助用药组(A组)和单纯全麻组(B组)。右美托咪定辅助用药组(A组)15min内静脉给予右美托咪定1μg/kg的负荷量,之后以0.2μg.kg-1.h-1的速度连续输注,手术结束前20min停止输注。记录全麻期间各时间点血流动力学变化及苏醒期躁动发生情况。结果:A组在麻醉诱导前心率下降明显,拔管前、后血流动力学平稳,苏醒期躁动明显减少(P<0.05)。结论:右美托咪定辅助用药能减少全麻苏醒期躁动。

The Effects of Dexmedetomidine on Emergence Agitation During General Anesthesia

Objective:To observe the effects of dexmedtomidine to emergence agitation during general anesthesia.Methods:60cases of patients accepted general anesthesia,were randomly divide into 2groups:group A(combine dexmedetomidine)and group B(only accepted general anesthesia),group A received dexmedetomidine 1μg/kg was injected 15minutes preoperatively followed by continuous infusion 0.2μg.kg-1.h-1.Operation before the end of the 20 minutes to stop infusion.Record each time point during general anesthesia hemodynamic changes and the incidence of emergence agitation.Results:The patients of group A had significantly decreased heart rate before induction of anesthesia,and stable hemodynamic before and after extubation,above all,significantly reduced emergence agitation(P< 0.05).Conclusion:Given dexmedetomidine during general anesthesia can reduce emergence agitation.